Benecol® effectively lowers LDL and total cholesterol

Plant stanol ester has been proven to reduce cholesterol in a number of randomised, placebo-controlled, double-blind clinical trials. Cholesterol-lowering effect has been proven:

  1. in healthy normocholesterolemic and hypercholesterolemic individuals
  2. in women, men and children of different ages
  3. in patients with
    • type 1 or type 2 diabetes or a metabolic syndrome
    • coronary heart disease
    • familial hypercholesterolemia
  4. as part of a typical diet as well as a strict cholesterol-lowering diet
  5. in combination with cholesterol-lowering statin therapy
  6. in populations from Asia, Europe, North America and Australia
  7. when Plant stanol ester has been incorporated into different types of foods, such as yoghurt mini-drinks, margarines and spreads, cereal products, spoonable yoghurts and soy-based products

Diabetes

Diabetics have an increased risk of developing CVD compared with healthy individuals. Therefore it is important to treat their risk factors as effectively as possible. Plant stanol ester in Benecol yogurt drinks effectively reduces serum cholesterol in both type 1 and type 2 diabetics1-4. Plant stanol ester is recommended to type 1 and type 2 diabetics for example in the guidelines of the American Diabetes Association and the American College of Cardiology Foundation.

Patients with coronary artery disease

When the patient already has cardiovascular disease, it is important to try to prevent the recurrence of a cardiac event by controlling all modifiable risk factors. Benecol is an effective means in lowering serum total and LDL cholesterol in combination of medication and other lifestyle modifications, also in secondary prevention.5-6

Familial hypercholesterolemia

Familial hypercholesterolemia (FH) is a genetic disease in which serum cholesterol level is elevated due to an inherited dysfunction in the LDL receptors. The efficacy and safety of using Benecol foods has been shown both in adults and in children with FH7-8.


1. Hallikainen et al. Atherosclerosis 2008
2. Hallikainen et al. Atherosclerosis 2011
3. Gylling & Miettinen, Diabetologia 1994
4. Gylling & Miettinen, J Lipid Res 1996
5. Gylling et al. Circulation 1997
6. Gylling et al. Menopause 2006
7. Vuorio et al. Arterioscler Thromb Vasc Biol 2000
8. Gylling et al. J Lipid Res 1995

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